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Is Matrixyl – 3000® the new Botox?

The chemical compound Pentapeptide-4 or Palmitoyl Pentapeptide-3 – popularly known as Matrixyl – 3000® – is being touted as the next wonder drug for a youth-obsessed generation. Claiming to reduce the appearance of wrinkles and fine lines in clinical trials by as much as 30 percent, it is increasingly finding its way into over-the-counter wrinkle creams and lotions. Is it really the miracle cure that we’ve all been waiting for or just hype to make us spend money on products we don’t really need? We spoke to the experts, and this is what we found.

The compound Matrixyl – 3000® is a combination of matrikines that include Palmitoyl Oligopeptide as well as Palmitoyl Tetrapeptide-7. Structurally, it is five linked amino acids that are, in turn, attached to a greasy acid. Matrixyl – 3000® works in two ways. First, it promotes the production of elastin, collagen, and glycoasaminoglycans in the skin, and second, it stimulates the creation of more fibroblast cells, which are responsible for collagen production. The result is increased elasticity, suppleness, and reduction of wrinkles in the areas where it’s used.

It is important to remember that, unless your chosen cream or lotion has the required concentration of Matrixyl – 3000®, the results may not be very effective. (The studies we refer to indicate using a minimum concentration of 3 percent.) It is also a fact that combining Matrixyl – 3000® with other ingredients can exponentially increase the overall benefits. A base of hyaluronic acid helps it penetrate deeper into the skin, while adding vitamins or other antioxidants can help get rid of damage-causing free radicals. Sunscreen inclusion is an obvious bonus as are herbal additives like green tea, which soothe and pamper the skin. The ultimate combination you pick should depend on your skin type and unique needs, but make sure you check for Matrixyl – 3000® the next time you go looking for a beauty cream!

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Lauren Stewart
By: Lauren Stewart

Lauren Stewart is a freelancer writer from Michigan. She enjoys writing about beauty, health and fitness! She is passionate about learning new ways to take control of her health and wellness and is a makeup and skincare junkie! You can contact her by emailing